2004 NOV 4 - (NewsRx.com & NewsRx.net) -- Scaffold topography alters cardiomyocyte network intracellular calcium dynamics.
According to recent research published in the American Journal of Physiology - Heart and Circulatory Physiology, "Structural and functional changes ensue in cardiac cell networks when cells are guided by three-dimensional scaffold topography.
"We report enhanced synchronous pacemaking activity in association with slow diastolic rise in intracellular Ca[superscript]2+ concentration ([Ca[superscript]2+][subscript]i) in cell networks grown on microgrooved scaffolds."
"Topography-driven changes in cardiac electromechanics were …
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